Cost-effectiveness of preimplantation genetic testing for aneuploidy for fresh donor oocyte cycles
نویسندگان
چکیده
منابع مشابه
What next for preimplantation genetic screening (PGS)? Experience with blastocyst biopsy and testing for aneuploidy.
Blastocysts more commonly have a normal karyotype than cleavage-stage embryos do. Moreover, blastocysts have also made a metabolic transition from catabolism and recycling of the oocyte's reserves and resources, processes that fuel the first 3 days of cleavage. Although not all blastocysts are karyotypically equal, it is still to be determined to what extent a mosaic karyotype might be a normal...
متن کاملWhat next for preimplantation genetic screening? Beyond aneuploidy.
Many published papers suggest a favourable impact of preimplantation genetic screening (PGS) on implantation and pregnancy rates, but more recent randomized studies have not confirmed, or could not conclude, that PGS actually improved implantation rates. Team inexperience in embryo screening has been mentioned as the origin of the discrepancies; thus some clinicians allege a need for more power...
متن کاملApplication of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles.
STUDY QUESTION Can next-generation sequencing (NGS) techniques be used reliably for comprehensive aneuploidy screening of human embryos from patients undergoing IVF treatments, with the purpose of identifying and selecting chromosomally normal embryos for transfer? SUMMARY ANSWER Extensive application of NGS in clinical preimplantation genetic screening (PGS) cycles demonstrates that this met...
متن کاملPreimplantation Genetic Testing
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متن کاملPreimplantation Genetic Testing
Preimplantation genetic testing (PGT) involves analysis of biopsied cells as part of an assisted reproductive procedure. It is generally considered to be divided into 2 categories. Preimplantation genetic diagnosis (PGD) is used to detect a specific inherited disorder and aims to prevent the birth of affected children in couples at high risk of transmitting a disorder. Preimplantation genetic s...
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ژورنال
عنوان ژورنال: F&S Reports
سال: 2021
ISSN: 2666-3341
DOI: 10.1016/j.xfre.2020.11.005